Blood Coagulation Test (Coagulogram)

A blood coagulation test (coagulogram) is used to detect disorders of blood clotting.

Indications for ordering a coagulogram include:

• blood coagulation disorders;
• examination during pregnancy;
• preoperative and postoperative periods;
• bleeding of various origins;
• varicose veins of the lower extremities;
• autoimmune diseases;
• liver diseases;
• cardiovascular disorders;
• use of oral contraceptives;
• monitoring during long-term therapy with indirect (oral) anticoagulants.

Impaired blood coagulation, especially increased clotting or hypercoagulability, may lead to serious health consequences, including myocardial infarction, stroke, and thrombosis.

Coagulogram Parameters

Bleeding Time

The period during which bleeding stops after a skin puncture. The normal value is 2–3 minutes. This test is performed to assess platelet function and the condition of the vascular wall.

APTT (Activated Partial Thromboplastin Time)

The time required for blood to clot, which depends on multiple coagulation factors and the level of heparin in the blood. This test is necessary for monitoring heparin therapy and adjusting dosage.

Prothrombin

A protein precursor of thrombin, which plays a key role in the blood coagulation process.

Fibrinogen

A plasma protein responsible for the formation of blood clots. It affects the erythrocyte sedimentation rate (ESR) and is considered an acute-phase inflammatory protein.

Antithrombin

A protein that inhibits thrombin and promotes the dissolution of blood clots. Reduced levels may lead to thrombosis and decreased effectiveness of heparin therapy.

Blood Coagulation Tests Are Available at Family Laboratory

• Complete coagulogram;
• Blood clotting time;
• Total fibrinogen;
• Prothrombin Index (%);
• INR (International Normalized Ratio), including prothrombin time and prothrombin index.